Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution

• Published in: Journal of applied physiology (1985) Vol. 60; no. 2; p. 532
• Main Authors: Rennard, S I, Basset, G, Lecossier, D, O'Donnell, K M, Pinkston, P, Martin, P G, Crystal, R G
• Format: Journal Article
• Language: English
• Published: United States 01.02.1986
• Subjects: Albumins - analysis; Body Fluids - cytology; Body Fluids - physiology; Bronchi - cytology; Bronchi - physiology; Cell Count; Diffusion; Epithelial Cells; Epithelium - physiology; Humans; Indicator Dilution Techniques; Pulmonary Alveoli - cytology; Pulmonary Alveoli - physiology; Therapeutic Irrigation; Urea

Bronchoalveolar lavage is a powerful technique for sampling the epithelial lining fluid (ELF) of the lower respiratory tract but also results in a significant dilution of that fluid. To quantify the apparent volume of ELF obtained by bronchoalveolar lavage, urea was used as an endogenous marker of E...