Differential expression of the Groucho-related genes 4 and 5 during early development of Xenopus laevis

• Published in: Mechanisms of development Vol. 91; no. 1; pp. 311 - 315
• Main Authors: Molenaar, Miranda, Brian, Elisabeth, Roose, Jeroen, Clevers, Hans, Destrée, Olivier
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.03.2000
• Subjects: Animals; Branchial arches; Cement gland; CNS; Co-Repressor Proteins; Cranial ganglia; Development; DNA-Binding Proteins; Ear vesicle; Embryo; Eye; Gene Expression Regulation, Developmental; Groucho; Neural crest; Pronephric duct; Pronephros; Repressor Proteins - genetics; Repressors; Somite; Tcf; Transcription factors; Wnt; Xenopus laevis; Xenopus laevis - embryology; Xenopus laevis - genetics; Xenopus Proteins; Embryo; Transcription factors; Branchial arches; Xenopus laevis; CNS; Pronephros; Pronephric duct; Groucho; Neural crest; Eye; Repressors; Tcf; Development; Ear vesicle; Cement gland; Somite; Wnt; Cranial ganglia

Recently, we demonstrated that the Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors ( Roose et al., 1998. Nature 395, 608–612). A long form of the Groucho-related genes, XGrg-4, was shown to repress axis formation in the Xenopus embryo, whereas a short form, XGrg...