Plagiochin E, an antifungal active macrocyclic bis(bibenzyl), induced apoptosis in Candida albicans through a metacaspase-dependent apoptotic pathway - Wu, Xiu-Zhen; Chang, Wen-Qiang; Cheng, Ai-Xia; Sun, Ling-Mei; Lou, Hong-Xiang (Biochimica et biophysica acta, 2010)
Keywords: Annexin A5 - drug effects; Annexin A5 - metabolism; Antifungal Agents - isolation & purification; Antifungal Agents - pharmacology; Apoptosis; Apoptosis - drug effects; Bridged-Ring Compounds - chemistry; Bridged-Ring Compounds - isolation & purification; Bridged-Ring Compounds - pharmacology; Candida albicans; Candida albicans - cytology; Candida albicans - drug effects; Candida albicans - enzymology; Candida albicans - genetics; Caspase Inhibitors; Cell Cycle - drug effects; Cell cycle arrest; DNA Primers; Flow Cytometry; Macrocyclic Compounds - chemistry; Macrocyclic Compounds - isolation & purification; Macrocyclic Compounds - pharmacology; Marchantia - chemistry; Metacaspase; Models, Molecular; Molecular Conformation; Plagiochin E; Protease Inhibitors - pharmacology; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal - genetics; RNA, Fungal - isolation & purification; Stilbenes - chemistry; Stilbenes - isolation & purification; Stilbenes - pharmacology; Candida albicans; Cell cycle arrest; Plagiochin E; Metacaspase; Apoptosis