Dietary anthocyanins balance immune signs in osteoarthritis and obesity - update of human in vitro studies and clinical trials

• Published in: Critical reviews in food science and nutrition Vol. 64; no. 9; pp. 2634 - 2672
• Main Authors: Pomilio, Alicia B., Szewczuk, Nicolas A., Duchowicz, Pablo R.
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 02.04.2024; Taylor & Francis Ltd
• Subjects: Anthocyanins; antioxidants; Arthritis; Assaying; Beans; Cell culture; Cell membranes; Cherries; Chondrocyte assays; Chondrocytes; Clinical trials; corn; Cultivars; cyanidin; delphinidin; dietary anthocyanins; dose response; flavonoids; food science; Glycosides; humans; immune system; Immunomodulation; In vivo methods and tests; Inflammation; Intracellular signalling; malvidin; Membrane permeability; Metabolites; nutraceuticals; nutrition; Obesity; Observational studies; Osteoarthritis; pomegranates; potatoes; preadipocyte assays; Preadipocytes; purple rice; rose hips; signaling pathways; Soybeans; dietary anthocyanins; signaling pathways; inflammation; nutraceuticals; osteoarthritis; Chondrocyte assays; immune system; clinical trials; preadipocyte assays; flavonoids; obesity
• ISSN: 1040-8398; 1549-7852; 1549-7852
• DOI: 10.1080/10408398.2022.2124948

Anthocyanins are known to change ligand-receptor bindings, cell membrane permeability, and intracellular signaling pathways. The beneficial effects of dietary anthocyanins have been chronologically demonstrated in interventional and observational studies, including fourteen human chondrocyte studies...