Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model

• Published in: Zoological research Vol. 44; no. 6; p. 1003
• Main Authors: Zhang, Zhongyun, Zhang, Ning, Lu, Xuancheng, Zhou, Min, Yan, Xiaoxiang, Gu, Weiqiong, Yang, Jingru, Zhang, Qin, Zhang, Cheng, Gong, Yuhuan, Jia, Mingjun, Zhang, Xiaoyu, Ning, Peng, Liu, Mei, Li, Xiaoyan, Shi, Xiaomeng, Liu, Wenjun, Gao, George F, Ning, Guang, Wang, Jiqiu, Bi, Yuhai
• Format: Journal Article
• Language: English
• Published: China 18.11.2023
• Subjects: Animals; Anti-Infective Agents; COVID-19 - veterinary; Diabetes Mellitus - veterinary; Disease Models, Animal; Heparin; Heparin, Low-Molecular-Weight; Humans; Insulin - therapeutic use; Mice; SARS-CoV-2; Antiviral therapy; SARS-CoV-2; Mouse model; Diabetes; Heparin

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity. However, the precise mechanisms responsible for the combined impact of corona virus disease 2019 (COVID-19) and diabetes have not yet...