Bile duct cell apoptosis is a rare event in primary biliary cirrhosis

• Published in: Digestive and liver disease Vol. 33; no. 2; pp. 151 - 156
• Main Authors: Ballardini, G., Guidi, M., Susca, M., Ghetti, S., Grassi, A., Lari, F., Fusconi, M., Zauli, D., Bianchi, F.B.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.03.2001
• Subjects: Adult; Apoptosis; Bile Ducts - pathology; Bile Ducts - physiopathology; Biopsy, Needle; Cells, Cultured; cirrhosis; DNA Fragmentation - physiology; Female; Fluorescent Antibody Technique; Hepatocytes - pathology; Humans; Immunohistochemistry; Liver Cirrhosis, Biliary - pathology; Liver Cirrhosis, Biliary - physiopathology; liver disease; Male; Middle Aged; Sensitivity and Specificity; liver disease; apoptosis; cirrhosis

Background. The frequency of apoptosis in bile duct cells of primary biliary cirrhosis is still unclear, spanning from rare to 50% in the various reports. Aim. To study bile duct cell apoptosis in stage I primary biliary cirrhosis lesions. Patients. Nine stage I-II biopsies with a total number of 26...