Glomerular hyperfiltration: A new marker of metabolic risk

• Published in: Kidney international Vol. 71; no. 8; pp. 816 - 821
• Main Authors: Tomaszewski, M., Charchar, F.J., Maric, C., McClure, J., Crawford, L., Grzeszczak, W., Sattar, N., Zukowska-Szczechowska, E., Dominiczak, A.F.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2007; Elsevier Limited
• Subjects: Adolescent; Adult; Age Factors; Biomarkers; blood pressure; Creatinine - blood; glomerular filtration rate; Glomerular Filtration Rate - physiology; Humans; Hyperglycemia - physiopathology; Kidney Diseases - complications; Kidney Diseases - physiopathology; leptin; Leptin - blood; Male; Metabolic Syndrome - complications; Metabolic Syndrome - epidemiology; Metabolic Syndrome - physiopathology; metabolism; Prevalence; renal function; Risk Factors; blood pressure; renal function; metabolism; glomerular filtration rate; leptin

Chronic kidney disease coexists with metabolic syndrome and this relationship may be apparent before overt manifestations of cardiovascular disease. To investigate early stages of the natural history of associations between renal function and metabolic syndrome, we phenotyped 1572 young (mean age=18...