Pesticide Exposure and Cholinesterase Levels in Migrant Farm Workers in Thailand

• Published in: Journal of agromedicine Vol. 22; no. 2; pp. 118 - 130
• Main Authors: Thetkathuek, Anamai, Yenjai, Pornthip, Jaidee, Wanlop, Jaidee, Patchana, Sriprapat, Poonsak
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 03.04.2017; Taylor & Francis Ltd
• Subjects: Adult; Aged; Agricultural Workers' Diseases - blood; Agricultural Workers' Diseases - enzymology; Agricultural Workers' Diseases - etiology; blood serum; Cambodia; Carbamate effect; cholinesterase; Cholinesterases - blood; chronic diseases; compliance; confidence interval; durians; Farms - manpower; Farmworkers; Female; Humans; hygiene; insecticides; Male; males; Medical screening; Middle Aged; migrant farm workers; Migrant workers; Occupational Exposure - adverse effects; Occupational safety; odds ratio; organophosphate effect; pesticide poisoning; Pesticides; Pesticides - toxicity; pineapples; Plantations; questionnaires; rambutans; regression analysis; risk; screening; sprayers; spraying; surveys; Thailand; Thailand fruit plantations; Transients and Migrants - statistics & numerical data; working conditions; Young Adult; Cambodia; Thailand; migrant farm workers; pesticide poisoning; Thailand fruit plantations; organophosphate effect; Carbamate effect
• DOI: 10.1080/1059924X.2017.1283276
• ISSN: 1059-924X; 1545-0813

Objectives: In this study, we examined the effects of pesticides in migrant farm workers from Cambodia after workplace exposure on fruit plantations in eastern Thailand. Methods: We studied 891 migrant farm workers employed on pineapple, durian, and rambutan plantations in Thailand. Data were collected via a detailed questionnaire survey and measurements of serum cholinesterase level (SChE). Results: The majority of subjects was male (57.7%), with an average age of 30.3 years. Most subjects (76.8%) were moderately aware of good industrial hygiene practices. SChE level was divided into four groups based on the results. Only 4.4% had normal levels of cholinesterase activity, 20.5% had slightly reduced levels, 58.5% had markedly reduced levels and were "at risk," and 16.6% who had highest levels of cholinesterase inhibition were deemed to be in an "unsafe" range. SChE was classified into two groups, SChE value of 87.5 was "normal" and <87.5 units/mL "abnormal." For the multiple logistic regression analysis of the abnormal SChE levels, the variables entered in the model included gender, period of insecticide use, the total area of plantation, frequency of spraying, period of daily insecticide spraying, and insecticide spraying method. The results indicated that the aOR (adjust odds ratio) for male migrant farm workers (95% confidence interval [CI]) was 1.58 (1.14, 2.17). The OR for farm migrant workers who worked on larger plantations of more than 39.5 acres (95% CI) was 2.69 (1.51, 4.82). Finally, the OR for the migrant farm workers who used a backpack sprayer (95% CI) was 2.07 (1.28, 3.34). Conclusions: These results suggest that health screening should be provided to migrant farm workers, especially those who spray pesticides on plantations of >39 acres, use a backpack sprayer, or have a low level of compliance with accepted industrial hygiene practices. These three classes of workers are at increased risk of chemical exposures and developing acute or chronic illness from pesticide exposures.