Database of bronchoalveolar lavage fluid proteins

Bronchoalveolar lavage during fiberoptic bronchoscopy is extensively used for investigating cellular and biochemical alterations of the epithelial lining fluid in various lung disorders. Two-dimensional electrophoresis (2-DE) offers the possibility to simultaneously display and analyze proteins cont...

Full description

Saved in:
Bibliographic Details
Published inJournal of Chromatography B Vol. 771; no. 1; pp. 221 - 236
Main Authors Noël-Georis, Isabelle, Bernard, Alfred, Falmagne, Paul, Wattiez, Ruddy
Format Book Review Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 05.05.2002
Subjects
Bronchoalveolar Lavage Fluid - chemistry
Databases, Protein
Electrophoresis, Gel, Two-Dimensional
Humans
Proteins
Proteins - chemistry
Proteins
Bronchoalveloar lavage
Reviews
Proteomics
Online AccessGet full text

Cover

More Information
Summary:Bronchoalveolar lavage during fiberoptic bronchoscopy is extensively used for investigating cellular and biochemical alterations of the epithelial lining fluid in various lung disorders. Two-dimensional electrophoresis (2-DE) offers the possibility to simultaneously display and analyze proteins contained in bronchoalveolar lavage fluid (BALF). We present the current status of 2-DE of BALF samples with an updated listing of the proteins already identified and of their level and/or posttranslational alterations in lung disorders. Alternatives to 2-DE of BALF samples and future prospects of proteomics to unravel lung functions and pathologies are discussed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1570-0232
1873-376X
DOI:10.1016/S1570-0232(02)00114-9