Sex Differences in the Inferior Parietal Lobule
The inferior parietal lobule (IPL) – a neocortical region and part of the heteromodal association cortex (HASC) – has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based up...
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| Published in | Cerebral cortex (New York, N.Y. 1991) Vol. 9; no. 8; pp. 896 - 901 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Oxford University Press
01.12.1999
Oxford Publishing Limited (England) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1047-3211 1460-2199 1460-2199 |
| DOI | 10.1093/cercor/9.8.896 |
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| Abstract | The inferior parietal lobule (IPL) – a neocortical region and part of the heteromodal association cortex (HASC) – has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal–gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes. |
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| AbstractList | The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal-gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes.The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal-gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes. The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal-gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes. |
| Author | Frederikse, Melissa E. Barta, Patrick Lu, Angela Aylward, Elizabeth Pearlson, Godfrey |
| Author_xml | – sequence: 1 givenname: Melissa E. surname: Frederikse fullname: Frederikse, Melissa E. organization: Division of Psychiatric Neuro-Imaging, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287 and – sequence: 2 givenname: Angela surname: Lu fullname: Lu, Angela organization: Division of Psychiatric Neuro-Imaging, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287 and – sequence: 3 givenname: Elizabeth surname: Aylward fullname: Aylward, Elizabeth organization: Division of Psychiatric Neuro-Imaging, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287 and – sequence: 4 givenname: Patrick surname: Barta fullname: Barta, Patrick organization: Division of Psychiatric Neuro-Imaging, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287 and – sequence: 5 givenname: Godfrey surname: Pearlson fullname: Pearlson, Godfrey organization: Division of Psychiatric Neuro-Imaging, Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287 and |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10601007$$D View this record in MEDLINE/PubMed |
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| Snippet | The inferior parietal lobule (IPL) – a neocortical region and part of the heteromodal association cortex (HASC) – has been hypothesized to exhibit sexual... The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual... |
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| SubjectTerms | Adult Female Functional Laterality Humans inferior parietal lobule Magnetic Resonance Imaging Male Middle Aged Parietal Lobe - anatomy & histology Sex Factors |
| Title | Sex Differences in the Inferior Parietal Lobule |
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