Additive toxicity arising from combined use of immune checkpoint inhibitors and tyrosine kinase inhibitors in patients with renal or endometrial carcinoma: Protocol for a rapid systematic review

• Published in: MethodsX Vol. 12; p. 102730
• Main Authors: Kelly, Shannon E., Wang, Xiaoqin, Hsieh, Shu-Ching, Abdul-Wahid, Aws, Derry, Melanie, Skidmore, Becky, Wells, George A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2024; Elsevier
• Subjects: Combined therapy; Immune checkpoint inhibitors; Medicine and Dentistry; Safety; Systematic review; Tyrosine kinase inhibitors; Systematic review; Immune checkpoint inhibitors; Safety; Combined therapy; Tyrosine kinase inhibitors

The combined use of immune checkpoint inhibitors and tyrosine kinase inhibitors (ICI/TKI) is an effective treatment strategy for some cancers. A better understanding of the potential additive toxicity for ICI/TKI combinations is needed to inform patient and provider treatment decisions. We aim to ev...