Evaluation of the urodynamic and hemodynamic effects of orally administered phenylpropanolamine and ephedrine in female dogs

• Published in: American journal of veterinary research Vol. 67; no. 4; pp. 723 - 730
• Main Authors: Carofiglio, F, Hamaide, A.J, Farnir, F, Balligand, M.H, Verstegen, J.P
• Format: Journal Article Web Resource
• Language: English
• Published: United States American Veterinary Medical Association 01.04.2006
• Subjects: administration & dosage; Administration, Oral; adverse effects; Animals; Beagle; Blood Pressure; Blood Pressure - drug effects; Blood Pressure - physiology; diastolic blood pressure; dog diseases; dogs; Dogs - physiology; dosage; drug effects; drug evaluation; ephedrine; Ephedrine - administration & dosage; Ephedrine - pharmacology; Female; females; Hemodynamics; Hemodynamics - drug effects; incontinence; Life sciences; Médecine vétérinaire & santé animale; oral administration; pharmacology; phenylpropanoids; Phenylpropanolamine; Phenylpropanolamine - administration & dosage; Phenylpropanolamine - pharmacology; physiology; Sciences du vivant; urethra; Urethra - drug effects; Urethra - physiology; urination; Urodynamics; Urodynamics - drug effects; Veterinary medicine & animal health

Objective-To compare the urodynamic and hemodynamic effects of different dosages of phenylpropanolamine and ephedrine and determine effective dosages in increasing urethral resistance in female dogs. Animals-20 sexually intact female Beagles. Procedure-Dogs were allocated into 4 groups and received...