LW-FQZip 2: a parallelized reference-based compression of FASTQ files

• Published in: BMC bioinformatics Vol. 18; no. 1; p. 179
• Main Authors: Huang, Zhi-An, Wen, Zhenkun, Deng, Qingjin, Chu, Ying, Sun, Yiwen, Zhu, Zexuan
• Format: Journal Article
• Language: English
• Published: England BioMed Central 20.03.2017
• Subjects: Acids; Algorithms; Alignment; Archives & records; Archiving; Arithmetic; Arithmetic coding; Assembling; Assembly; Bioinformatics; Compression; Computer programs; Conserved sequence; Data compression; Data Compression - methods; Data transfer (computers); Data transmission; Deoxyribonucleic acid; DNA; DNA methylation; DNA sequencing; Filters; Fragmentation; Gene mapping; Genetic transformation; Genomes; High-Throughput Nucleotide Sequencing - methods; Homology; Mapping; Matching; Mathematical models; Metadata; Methods; Nucleotide sequence; Nucleotides; Palindromes; Porosity; Probability theory; Quality; Redundancy; Sequence Alignment - methods; Sequence Analysis, DNA - methods; Silver; Software; Statistical analysis; Streams; Sun; Weight reduction; Sequencing data compression; Reference- based compression; High-throughput sequencing; Sequence alignment

The rapid progress of high-throughput DNA sequencing techniques has dramatically reduced the costs of whole genome sequencing, which leads to revolutionary advances in gene industry. The explosively increasing volume of raw data outpaces the decreasing disk cost and the storage of huge sequencing da...