Reduced GABA levels correlate with cognitive impairment in patients with relapsing-remitting multiple sclerosis - Cao, Guanmei; Edden, Richard A. E.; Gao, Fei; Li, Hao; Gong, Tao; Chen, Weibo; Liu, Xiaohui; Wang, Guangbin; Zhao, Bin (European radiology, 2018)
Keywords: Abnormalities; Adult; Brain; Brain - metabolism; Case-Control Studies; Cognitive ability; Cognitive Dysfunction - etiology; Cognitive Dysfunction - metabolism; Cortex (cingulate); Diagnostic Radiology; Female; gamma-Aminobutyric Acid - metabolism; Gyrus Cinguli - metabolism; Hippocampus; Humans; Imaging; Impairment; Interferon; Internal Medicine; Interventional Radiology; Magnetic Resonance; Magnetic Resonance Imaging; Magnetic resonance spectroscopy; Magnetic Resonance Spectroscopy - methods; Male; Medicine; Medicine & Public Health; Middle Aged; Multiple sclerosis; Multiple Sclerosis, Relapsing-Remitting - metabolism; Multiple Sclerosis, Relapsing-Remitting - psychology; Neuropsychological Tests; Neuroradiology; Neurotransmission; Pathogenesis; Patients; Prefrontal cortex; Prefrontal Cortex - metabolism; Radiology; Severity of Illness Index; Spectroscopy; Spectrum analysis; Temporal Lobe - metabolism; Ultrasound; γ-Aminobutyric acid; GABA; MEGA-PRESS; Multiple sclerosis; H-MRS; Cognitive impairment; 1H-MRS