Quantification of total concentration of thiol functional groups in environmental samples by titration with monobromo(trimethylammonio)bimane and determination with tandem mass spectrometry

• Published in: Talanta (Oxford) Vol. 218; p. 121109
• Main Authors: Huynh, Khoa, Liem-Nguyen, Van, Feng, Caiyan, Lindberg, Richard, Björn, Erik
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2020
• Subjects: derivatization; Environmental samples; monobromo(trimethylammonio)bimane; monobromo(trimethylammonio)bimane derivatization; Natural organic matter; Tandem mass spectrometry; Thiol; Tandem mass spectrometry; monobromo(trimethylammonio)bimane derivatization; Thiol; Environmental samples; Natural organic matter

Thiol compounds (R–SH) have many important biological functions and are principal controls of the speciation of several toxic metals in the environment. However, determining the concentration of thiols associated with environmental matrices is challenging due to the compounds’ low abundance and inte...