Adaptive Immune Responses following Senecavirus A Infection in Pigs

• Published in: Journal of virology Vol. 92; no. 3
• Main Authors: Maggioli, Mayara F, Lawson, Steve, de Lima, Marcelo, Joshi, Lok R, Faccin, Tatiane C, Bauermann, Fernando V, Diel, Diego G
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2018
• Subjects: Adaptive Immunity; Animals; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Foot-and-Mouth Disease - pathology; Host-Pathogen Interactions; Immunity, Cellular; Immunity, Humoral; Pathogenesis and Immunity; Picornaviridae; Swine; Swine Vesicular Disease - pathology; T-Lymphocytes - immunology; Viremia - immunology; Viremia - veterinary; vesicular disease; SVV; virus-host interactions; Seneca Valley virus; SVA

Senecavirus A (SVA), an emerging picornavirus of swine, causes vesicular disease (VD) that is clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Many aspects of SVA interactions with the host and the host immune responses to infection, however, remain unknown. In the present stu...