Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles

• Published in: American journal of physiology: endocrinology and metabolism Vol. 290; no. 4; pp. E739 - E745
• Main Authors: Lundahl, Bjorn, Skoglund-Andersson, Camilla, Caslake, Muriel, Bedford, Dorothy, Stewart, Philip, Hamsten, Anders, Packard, Christopher J, Karpe, Fredrik
• Format: Journal Article
• Language: English
• Published: United States 01.04.2006
• Subjects: Adult; Apolipoprotein B-100; Apolipoproteins B - blood; Apolipoproteins B - metabolism; Apolipoproteins B - secretion; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cohort Studies; Genotype; Humans; Leucine - metabolism; Lipoproteins - blood; Lipoproteins - metabolism; Lipoproteins, IDL; Lipoproteins, LDL - blood; Lipoproteins, LDL - metabolism; Male; Middle Aged; Models, Biological; Phenotype; Polymorphism, Genetic - physiology; Sweden; Sweden

1 Atherosclerosis Research Unit, King Gustaf V Research Institute, Department of Medicine, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden 2 Department of Pathological Biochemistry, University of Glasgow, Royal Infirmary, Glasgow 3 Oxford Centre for Diabetes, Endocrinology and Metabolis...