Multiple-Dose Pharmacokinetics, Pharmacodynamics, and Safety of the Urotensin-II Receptor Antagonist Palosuran in Healthy Male Subjects - Sidharta, Patricia N; van Giersbergen, Paul L M; Dingemanse, Jasper (Pharmacology, 2018)
Keywords: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Patient Safety; Potassium - urine; Quinolines - administration & dosage; Quinolines - adverse effects; Quinolines - blood; Quinolines - pharmacokinetics; Receptors, G-Protein-Coupled - antagonists & inhibitors; Sodium - urine; Urea - administration & dosage; Urea - adverse effects; Urea - analogs & derivatives; Urea - blood; Urea - pharmacokinetics; Urotensin-II; Palosuran; Pharmacodynamics; Urotensin-II receptor antagonist; Pharmacokinetics