Mechanisms and therapeutic potential of chinonin in nervous system diseases

The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the pr...

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Published inJournal of asian natural products research Vol. 26; no. 12; pp. 1405 - 1420
Main Authors Hui, Zhang, Lai-Fa, Wang, Xue-Qin, Wang, Ling, Deng, Bin-Sheng, He, Li, Jian-Ming
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 01.12.2024
Taylor & Francis Ltd
Subjects
Anemarrhena
Anemarrhena - chemistry
Animals
Anti-Inflammatory Agents - chemistry
Anti-Inflammatory Agents - pharmacology
Anti-Inflammatory Agents - therapeutic use
antioxidants
Antioxidants - chemistry
Antioxidants - pharmacology
brain damage
Brain injury
Flavonoids
Head injuries
Humans
immunity
mitochondria
Molecular Structure
Nervous system
Nervous system diseases
Nervous System Diseases - drug therapy
Neurological diseases
Neuroprotection
Neuroprotective Agents - chemistry
Neuroprotective Agents - pharmacology
Neuroprotective Agents - therapeutic use
Pharmacology
protective effect
rhizomes
therapeutics
Xanthones - chemistry
Xanthones - pharmacology
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Abstract The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.
AbstractList The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. “Chinonin” OR “Mangiferin” AND “Nervous system diseases” OR “Neuroprotection” was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.
The flavonoid compound chinonin is one of the main active components of with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.
The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.
Author Hui, Zhang
Lai-Fa, Wang
Bin-Sheng, He
Li, Jian-Ming
Ling, Deng
Xue-Qin, Wang
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CitedBy_id crossref_primary_10_1002_jbt_70027
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Snippet The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and...
The flavonoid compound chinonin is one of the main active components of with multiple activities, including anti-inflammatory and antioxidant properties,...
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SubjectTerms Anemarrhena
Anemarrhena - chemistry
Animals
Anti-Inflammatory Agents - chemistry
Anti-Inflammatory Agents - pharmacology
Anti-Inflammatory Agents - therapeutic use
antioxidants
Antioxidants - chemistry
Antioxidants - pharmacology
brain damage
Brain injury
Flavonoids
Head injuries
Humans
immunity
mitochondria
Molecular Structure
Nervous system
Nervous system diseases
Nervous System Diseases - drug therapy
Neurological diseases
Neuroprotection
Neuroprotective Agents - chemistry
Neuroprotective Agents - pharmacology
Neuroprotective Agents - therapeutic use
Pharmacology
protective effect
rhizomes
therapeutics
Xanthones - chemistry
Xanthones - pharmacology
Title Mechanisms and therapeutic potential of chinonin in nervous system diseases
URI https://www.tandfonline.com/doi/abs/10.1080/10286020.2024.2371040
https://www.ncbi.nlm.nih.gov/pubmed/38975978
https://www.proquest.com/docview/3126606184
https://www.proquest.com/docview/3076766761
https://www.proquest.com/docview/3154155504
Volume 26
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