A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS

• Published in: Analyst (London) Vol. 140; no. 1; pp. 71 - 73
• Main Authors: Nakata, Katsunori, Ichibangase, Tomoko, Saitoh, Ryoichi, Ishigai, Masaki, Imai, Kazuhiro
• Format: Journal Article
• Language: English
• Published: England 07.01.2015
• Subjects: Biotechnology; Carcinoma, Hepatocellular - pathology; Chromatography, Liquid; Fingerprints; Fluorescent Dyes - chemistry; Human; Humans; Liver Neoplasms - pathology; Neoplasm Proteins - analysis; Peptide Mapping; Proteins; Proteomics; Tandem Mass Spectrometry

A proteomics profile analysis was performed on a human hepatocyte carcinoma cell line (HepaRG) by using the FD-LC-MS/MS method. One hundred and fifty-eight proteins were newly identified for the first time of which 10 were found to be specific to human hepatocytes. These proteins are a "proteom...