Alginate-chitosan Hydrogel Patch with Beta-glucan Nanoemulsion for Antibacterial Applications
Natural polymer materials have high biocompatibility and are not toxic because they can decompose into metabolites in the body; thus, they are widely used as medical polymer materials as well as porous support materials. As a biopolymer, alginate has a negative charge; in contrast, chitosan has a po...
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Published in | Biotechnology and bioprocess engineering Vol. 26; no. 1; pp. 71 - 77 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Seoul
The Korean Society for Applied Biological Chemistry
01.02.2021
Springer Nature B.V 한국생물공학회 |
Subjects | |
Online Access | Get full text |
ISSN | 1226-8372 1976-3816 |
DOI | 10.1007/s12257-020-0177-4 |
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Abstract | Natural polymer materials have high biocompatibility and are not toxic because they can decompose into metabolites in the body; thus, they are widely used as medical polymer materials as well as porous support materials. As a biopolymer, alginate has a negative charge; in contrast, chitosan has a positive charge. Therefore, when the two substances are mixed, they form a relatively stable structure by ionic bonding. Beta-glucan is known to contribute to material stability and have high skin penetration, skin moisturizing and soothing effects, and burn and wound healing effects. In this study, antimicrobial activity was assessed by preparing alginate-chitosan hydrogel patches containing beta-glucan nanoemulsions. This could contribute to the development of wound dressings with antibacterial properties. |
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AbstractList | Natural polymer materials have high biocompatibility and are not toxic because they can decompose into metabolites in the body; thus, they are widely used as medical polymer materials as well as porous support materials. As a biopolymer, alginate has a negative charge; in contrast, chitosan has a positive charge. Therefore, when the two substances are mixed, they form a relatively stable structure by ionic bonding. Beta-glucan is known to contribute to material stability and have high skin penetration, skin moisturizing and soothing effects, and burn and wound healing effects. In this study, antimicrobial activity was assessed by preparing alginate-chitosan hydrogel patches containing beta-glucan nanoemulsions. This could contribute to the development of wound dressings with antibacterial properties. Natural polymer materials have high biocompatibility and are not toxic because they can decompose into metabolites in the body; thus, they are widely used as medical polymer materials as well as porous support materials. As a biopolymer, alginate has a negative charge; in contrast, chitosan has a positive charge. Therefore, when the two substances are mixed, they form a relatively stable structure by ionic bonding. Beta-glucan is known to contribute to material stability and have high skin penetration, skin moisturizing and soothing effects, and burn and wound healing effects. In this study, antimicrobial activity was assessed by preparing alginate-chitosan hydrogel patches containing beta-glucan nanoemulsions. This could contribute to the development of wound dressings with antibacterial properties. KCI Citation Count: 0 |
Author | Tanaka, Masayoshi Choi, Yonghyun Choi, Jonghoon Lee, Keun-Heon Jang, Jaehee Koo, Hyung-Jun |
Author_xml | – sequence: 1 givenname: Yonghyun surname: Choi fullname: Choi, Yonghyun organization: School of Integrative Engineering, Chung-Ang University – sequence: 2 givenname: Jaehee surname: Jang fullname: Jang, Jaehee organization: School of Integrative Engineering, Chung-Ang University – sequence: 3 givenname: Hyung-Jun surname: Koo fullname: Koo, Hyung-Jun organization: Department of Chemical and Biomolecular Engineering, Seoul National University of Science and Technology – sequence: 4 givenname: Masayoshi surname: Tanaka fullname: Tanaka, Masayoshi organization: Department of Chemical Science and Engineering, Tokyo Institute of Technology – sequence: 5 givenname: Keun-Heon surname: Lee fullname: Lee, Keun-Heon organization: Humas – sequence: 6 givenname: Jonghoon surname: Choi fullname: Choi, Jonghoon email: nanomed@cau.ac.kr organization: School of Integrative Engineering, Chung-Ang University |
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Title | Alginate-chitosan Hydrogel Patch with Beta-glucan Nanoemulsion for Antibacterial Applications |
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