pH-sensitive cationic guar gum/poly (acrylic acid) polyelectrolyte hydrogels: Swelling and in vitro drug release

• Published in: Carbohydrate polymers Vol. 69; no. 4; pp. 774 - 783
• Main Authors: Huang, Yihong, Yu, Huiqun, Xiao, Chaobo
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 02.07.2007; Elsevier Science
• Subjects: acrylic acid; Applied sciences; Biological and medical sciences; Cationic guar gum; cations; colon; Controlled release; differential scanning calorimetry; drug delivery systems; electrostatic interactions; equations; Exact sciences and technology; Fourier transform infrared spectroscopy; General pharmacology; guar gum; hydrocolloids; Hydrogels; in vitro studies; ketoprofen; Medical sciences; Natural polymers; Pharmaceutical technology. Pharmaceutical industry; pharmacokinetics; Pharmacology. Drug treatments; Physicochemistry of polymers; Poly (acrylic acid); polymerization; polymers; scanning electron microscopy; Starch and polysaccharides; Swelling; swelling (materials); synthesis; Cationic guar gum; Hydrogels; Swelling; Controlled release; Poly (acrylic acid); Composition effect; Drug carrier; Etherification; Ketoprofen; Mechanism; Colloidal gel; Intermolecular interaction; Photopolymerization; Guar gum; pH; Release; Modified material; Control release polymer; Experimental study; In vitro; Quaternary ammonium compound; Non steroidal antiinflammatory agent; Polyelectrolyte; Chemical modification; Morphology; Preparation; Acrylic acid polymer; Oside polymer; Kinetics; Quaternary ammonium polymer

Novel polyelectrolyte hydrogels (coded as GA) based on cationic guar gum (CGG) and acrylic acid monomer by photoinitiated free-radical polymerization were synthesized with various feed compositions. Fourier transform infrared spectra (FTIR), scanning electron microscopy (SEM), and differential scann...