Mouse polyQ database: a new online resource for research using mouse models of neurodegenerative diseases

• Published in: Molecular brain Vol. 8; no. 1; p. 69
• Main Authors: Szlachcic, Wojciech J, Switonski, Pawel M, Kurkowiak, Małgorzata, Wiatr, Kalina, Figiel, Maciej
• Format: Journal Article
• Language: English
• Published: England BioMed Central 29.10.2015
• Subjects: Animals; Databases, Protein; Disease Models, Animal; Internet; Mice; Neurodegenerative Diseases - pathology; Peptides - metabolism; Phenotype; Search Engine; User-Computer Interface

The polyglutamine (polyQ) family of disorders comprises 9 genetic diseases, including several types of ataxia and Huntington disease. Approximately two decades of investigation and the creation of more than 130 mouse models of polyQ disorders have revealed many similarities between these diseases. T...