Effectiveness of statins in reducing the rate of severe sepsis: a retrospective evaluation

• Published in: Pharmacotherapy Vol. 27; no. 1; p. 20
• Main Authors: Martin, Christopher P, Talbert, Robert L, Burgess, David S, Peters, Jay I
• Format: Journal Article
• Language: English
• Published: United States 01.01.2007
• Subjects: Aged; Cohort Studies; Female; Hospitals, University; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Male; Middle Aged; Retrospective Studies; Sepsis - epidemiology; Sepsis - prevention & control; Texas - epidemiology; Texas

To determine whether use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) is associated with a reduced rate of severe sepsis, and to further characterize the effect of statins on the frequency of organ dysfunction in patients with severe sepsis. Retrospective cohort study. Uni...