Differential expression of the seven‐pass transmembrane cadherin genes Celsr1‐3 and distribution of the Celsr2 protein during mouse development

• Published in: Developmental dynamics Vol. 223; no. 3; pp. 321 - 332
• Main Authors: Shima, Yasuyuki, Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Chisaka, Osamu, Takeichi, Masatoshi, Uemura, Tadashi
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.03.2002
• Subjects: Animals; Blotting, Western; cadherin superfamily; Cadherins - biosynthesis; Cadherins - metabolism; Cell Line; Cells, Cultured; Celsr; Central Nervous System - embryology; Chromosome Mapping; Cloning, Molecular; Crosses, Genetic; Ear, Inner - metabolism; Fetal Proteins; Flamingo; gene mapping; Hippocampus - metabolism; Humans; Immunoblotting; immunohistochemistry; In Situ Hybridization; Mice; Models, Genetic; mouse development; Neurons - metabolism; Purkinje Cells - metabolism; Receptors, Cell Surface - biosynthesis; Receptors, G-Protein-Coupled; RNA - metabolism; RNA, Messenger - metabolism; Time Factors; Tissue Distribution; Transfection

Drosophila Flamingo (Fmi) is an evolutionally conserved seven‐pass transmembrane receptor of the cadherin superfamily. Fmi plays multiple roles in patterning neuronal processes and epithelial planar cell polarity. To explore the in vivo roles of Fmi homologs in mammals, we previously cloned one of t...