Effect of intra‐observer variation in prostate volume measurement on prostate‐specific antigen density calculations among prostate cancer active surveillance participants

• Published in: BJU international Vol. 108; no. 11; pp. 1739 - 1742
• Main Authors: Ko, Joan S., Landis, Patricia, Carter, H. Ballentine, Partin, Alan W.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.12.2011; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: active surveillance; Aged; Aging; Androgens; Biological and medical sciences; Biopsy - methods; Cohort Studies; Gynecology. Andrology. Obstetrics; Humans; Male; Male genital diseases; Medical sciences; Men; Middle Aged; Nephrology. Urinary tract diseases; Observer Variation; Organ Size; Patient Selection; Prostate - metabolism; Prostate - pathology; Prostate cancer; prostate volume; Prostate-Specific Antigen - metabolism; prostate‐specific antigen density; Prostatic Neoplasms - diagnosis; Therapy; Tumors; Tumors of the urinary system; ultrasonography; Ultrasonography, Interventional - methods; Urinary tract. Prostate gland; Nephrology; Prostate disease; ultrasonography; Variations; Tumoral marker; Density; Urology; Prostate specific antigen; Intraindividual comparison; Volume measurement; Calculation; Urogenital system; Male genital diseases; Sonography; Urinary system disease; prostate-specific antigen density; prostate volume; Malignant tumor; Surveillance; Volume; Echography; Prostate cancer; Prostate; active surveillance; Cancer
• ISSN: 1464-4096; 1464-410X; 1464-410X
• DOI: 10.1111/j.1464-410X.2011.10223.x

Study Type – Diagnostic (exploratory cohort) Level of Evidence 2b What’s known on the subject? and What does the study add? The Epstein criteria, which utilize prostate specific antigen density (PSAD) benchmarks, are recognized to be a reasonable method of selecting men for active surveillance of pr...