Extended, One‐stage Callosal Section for Treatment of Refractory Secondarily Generalized Epilepsy in Patients with Lennox–Gastaut and Lennox‐like Syndromes

• Published in: Epilepsia (Copenhagen) Vol. 47; no. 2; pp. 371 - 374
• Main Authors: Cukiert, Arthur, Burattini, Jose Augusto, Mariani, Pedro Paulo, Câmara, Ródio Brandão, Seda, Lauro, Baldauf, Cristine Mella, Argentoni, Meire, Baise‐Zung, Carla, Forster, Cássio Roberto, Mello, Valeria Antakli
• Format: Journal Article
• Language: English
• Published: 350 Main Street , Malden , MA 02148 , USA and 9600 Garsington Road , Oxford , OX4 2XG , England Blackwell Publishing Inc 01.02.2006; Blackwell
• Subjects: Anticonvulsants. Antiepileptics. Antiparkinson agents; Attention - physiology; Biological and medical sciences; Brain Diseases - diagnosis; Brain Diseases - etiology; Brain Diseases - psychology; Callosotomy; Child; Cognition Disorders - diagnosis; Cognition Disorders - etiology; Cognition Disorders - psychology; Complex syndromes; Corpus Callosum - surgery; Electroencephalography; Epilepsy - surgery; Epilepsy, Generalized - surgery; Female; Follow-Up Studies; Functional Laterality - physiology; Generalized epilepsy; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Medical genetics; Medical sciences; Nervous system (semeiology, syndromes); Neurology; Neuropharmacology; Neurosurgical Procedures - methods; Outcome; Pharmacology. Drug treatments; Postoperative Complications - diagnosis; Postoperative Complications - etiology; Postoperative Complications - psychology; Surgery; Technique; Treatment Outcome; Lennox syndrome; Human; Nervous system diseases; Prognosis; Epilepsy; Section; Corpus callosum; Cerebral disorder; Refractory; Callosotomy-Surgery-Generalized epilepsy-Technique-Outcome; Treatment; Surgery; Central nervous system disease; Technique

Purpose: We report on the efficacy and safety of extended one‐stage callosal section performed in a large and homogeneous series of patients. Methods: Seventy‐six patients with Lennox–Gastaut (n = 28) and Lennox‐like (n = 48) syndrome were studied (42 male patients; mean age, 11.2 years). All patien...