Diagnostic accuracy of exhaled nitric oxide for the non-invasive identification of patients with fibrotic metabolic dysfunction-associated steatohepatitis

• Published in: Annals of medicine (Helsinki) Vol. 56; no. 1; p. 2410408
• Main Authors: Zhang, Huai, Huang, Ou-Yang, Chen, Li-Li, Zhang, Ni, Chen, Wen-Ying, Zheng, Wen, Zhang, Xin-Lei, Jin, Xiao-Zhi, Chen, Sui-Dan, Targher, Giovanni, Byrne, Christopher D., Zheng, Ming-Hua
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.12.2024; Taylor & Francis Group
• Subjects: Adult; Biomarkers - analysis; Biomarkers - metabolism; breath test; Breath Tests - methods; Exhalation; Exhaled nitric oxide; Fatty Liver - diagnosis; Fatty Liver - metabolism; Female; fibrotic MASH; Hepatology; Humans; Liver Cirrhosis - diagnosis; Liver Cirrhosis - metabolism; Male; Middle Aged; Nitric Oxide - analysis; Nitric Oxide - metabolism; Non-alcoholic Fatty Liver Disease - diagnosis; Non-alcoholic Fatty Liver Disease - metabolism; ROC Curve; Sensitivity and Specificity; breath test; fibrotic MASH; Exhaled nitric oxide

Fibrotic metabolic dysfunction-associated steatohepatitis (MASH) is a condition at risk of progressing to advanced liver disease. We examined whether an innovative exhaled nitric oxide (eNO) breath test (BT) can accurately diagnose fibrotic MASH without requiring blood tests. One hundred and forty-s...