A mushroom lectin from ascomycete Cordyceps militaris

• Published in: Biochimica et biophysica acta Vol. 1770; no. 5; pp. 833 - 838
• Main Authors: Jung, Eui Cha, Kim, Ki Don, Bae, Chan Hyung, Kim, Ju Cheol, Kim, Dae Kyong, Kim, Ha Hyung
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2007
• Subjects: Amino Acid Sequence; Animals; Ascomycete; Ascomycota - chemistry; Chromatography, Gel; Circular Dichroism; Cordyceps - chemistry; Cordyceps militaris; Electrophoresis, Polyacrylamide Gel; Freezing; Hemagglutination - drug effects; Hemagglutination Tests; Hydrogen-Ion Concentration; Lectin; Mice; Mitosis - drug effects; Molecular Sequence Data; Molecular Weight; Mushroom; Oxidation-Reduction; Plant Lectins - chemistry; Plant Lectins - isolation & purification; Plant Lectins - metabolism; Plant Lectins - pharmacology; Protein Binding; Protein Structure, Secondary; Rats; Sialoglycoproteins - pharmacology; Silver Staining; Spleen - cytology; Spleen - drug effects; Lectin; Cordyceps militaris; Ascomycete; Mushroom

A mushroom lectin has been purified from ascomycete Cordyceps militaris, which is one of the most popular mushrooms in eastern Asia used as a nutraceutical and in traditional Chinese medicine. This lectin, designated CML, exhibited hemagglutination activity in mouse and rat erythrocytes, but not in...