Therapeutic Strategies for Rheumatoid Arthritis

• Published in: The New England journal of medicine Vol. 350; no. 25; pp. 2591 - 2602
• Main Authors: Wood, Alastair JJ, O'Dell, James R
• Format: Journal Article
• Language: English
• Published: Boston, MA Massachusetts Medical Society 17.06.2004
• Subjects: Adrenal Cortex Hormones - therapeutic use; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Antirheumatic Agents - therapeutic use; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - drug therapy; Arthritis, Rheumatoid - therapy; Autoantibodies - blood; Autoimmune diseases; Biological and medical sciences; Citrulline - immunology; Comorbidity; Cytokines; Diseases of the osteoarticular system; Drug Therapy, Combination; General aspects; Humans; Inflammatory joint diseases; Medical research; Medical sciences; Prognosis; Rheumatoid arthritis; Rheumatoid Factor - blood; Medicine; Immunopathology; Chronic; Treatment; Rheumatoid arthritis; Diseases of the osteoarticular system; Autoimmune disease; Strategy; Inflammatory joint disease

A better understanding of the pathophysiology of rheumatoid arthritis, together with influential trials aimed at treating early stages of the disease, has altered therapy. This article considers approaches that have resulted in markedly better clinical outcomes, including early diagnosis and treatme...