[Zn(l-proline)2] Catalyzed One-Pot Synthesis of Propargylamines Under Solvent-Free Conditions

A simple, one-pot, three-component, green synthesis of a wide range of propargylamines is reported by A 3 -coupling (aldehyde, alkyne and amine) via C–H activation of alkynes using [Zn( l -proline) 2 ] as an efficient and reusable heterogeneous catalyst. High catalytic activity was achieved in compa...

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Bibliographic Details
Published inCatalysis letters Vol. 148; no. 9; pp. 2675 - 2682
Main Authors Layek, Samaresh, Agrahari, Bhumika, Kumari, Shweta, Anuradha, Pathak, Devendra D.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.09.2018
Springer Nature
Springer
Springer Nature B.V
Subjects
Aldehydes
Alkynes
Catalysis
Catalysts
Catalytic activity
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry, Physical
Industrial Chemistry/Chemical Engineering
Organometallic Chemistry
Physical Chemistry
Physical Sciences
Proline
Reagents
Science & Technology
Solvents
Zinc (Metal)
C–C and C–N coupling reaction
proline
C–H activation
Zn
Propargylamines
]
ALDEHYDE
C-C and C-N coupling reaction
AMINE
ALKYNE
GREEN
HIGHLY EFFICIENT
Zn(L-proline)
REUSABLE CATALYST
NANOPARTICLES
C-H activation
COUPLING REACTION
RECYCLABLE CATALYST
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Summary:A simple, one-pot, three-component, green synthesis of a wide range of propargylamines is reported by A 3 -coupling (aldehyde, alkyne and amine) via C–H activation of alkynes using [Zn( l -proline) 2 ] as an efficient and reusable heterogeneous catalyst. High catalytic activity was achieved in comparatively low temperature under solvent-free conditions. All reactions were carried out in an open atmosphere without the use of any co-catalyst/additive. Graphical Abstract
ISSN:1011-372X
1572-879X
DOI:10.1007/s10562-018-2449-6