Kernicterus and G6PD deficiency--a case series from Oman

The relationship between glucose-6 phosphate dehydrogenase (G6PD) deficiency and jaundice in the newborn period is well recognized. However, there is concern about the increasing incidence of kernicterus being reported worldwide, especially due to unrecognized G6PD deficiency and early discharge fro...

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Bibliographic Details
Published inJournal of tropical pediatrics (1980) Vol. 49; no. 2; p. 74
Main Authors Nair, P Arun Kumar, Al Khusaiby, Saleh Mohammad
Format Journal Article
LanguageEnglish
Published England 01.04.2003
Subjects
Female
Glucosephosphate Dehydrogenase Deficiency - complications
Humans
Infant, Newborn
Jaundice, Neonatal - complications
Jaundice, Neonatal - diagnosis
Jaundice, Neonatal - prevention & control
Kernicterus - etiology
Male
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Summary:The relationship between glucose-6 phosphate dehydrogenase (G6PD) deficiency and jaundice in the newborn period is well recognized. However, there is concern about the increasing incidence of kernicterus being reported worldwide, especially due to unrecognized G6PD deficiency and early discharge from hospital after birth. We report a case series of kernicterus from a set-up where the high prevalence rate of G6PD deficiency is known. Fourteen cases of kernicterus were seen during a time period of 6 years, 71 per cent of them had G6PD deficiency. Recent literature is reviewed and possible preventive measures in the light of current information and practices are suggested.
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/49.2.74