Modulation of the inter-hemispheric processing of semantic information during normal aging. A divided visual field experiment

• Published in: Neuropsychologia Vol. 93; no. Pt B; pp. 425 - 436
• Main Authors: Hoyau, E., Cousin, E., Jaillard, A., Baciu, M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2016; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Aging; Aging - physiology; Aging - psychology; Analysis of Variance; DVF; Female; Functional Laterality; Hemispheric Specialization; Humanities and Social Sciences; Humans; Language; Life Sciences; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Pattern Recognition, Visual - physiology; Photic Stimulation - methods; Reaction Time; Semantics; Aging; Language; Semantics; DVF; Hemispheric Specialization
• DOI: 10.1016/j.neuropsychologia.2015.12.027
• ISSN: 0028-3932

We evaluated the effect of normal aging on the inter-hemispheric processing of semantic information by using the divided visual field (DVF) method, with words and pictures. Two main theoretical models have been considered, (a) the HAROLD model which posits that aging is associated with supplementary recruitment of the right hemisphere (RH) and decreased hemispheric specialization, and (b) the RH decline theory, which assumes that the RH becomes less efficient with aging, associated with increased LH specialization. Two groups of subjects were examined, a Young Group (YG) and an Old Group (OG), while participants performed a semantic categorization task (living vs. non-living) in words and pictures. The DVF was realized in two steps: (a) unilateral DVF presentation with stimuli presented separately in each visual field, left or right, allowing for their initial processing by only one hemisphere, right or left, respectively; (b) bilateral DVF presentation (BVF) with stimuli presented simultaneously in both visual fields, followed by their processing by both hemispheres. These two types of presentation permitted the evaluation of two main characteristics of the inter-hemispheric processing of information, the hemispheric specialization (HS) and the inter-hemispheric cooperation (IHC). Moreover, the BVF allowed determining the driver-hemisphere for processing information presented in BVF. Results obtained in OG indicated that: (a) semantic categorization was performed as accurately as YG, even if more slowly, (b) a non-semantic RH decline was observed, and (c) the LH controls the semantic processing during the BVF, suggesting an increased role of the LH in aging. However, despite the stronger involvement of the LH in OG, the RH is not completely devoid of semantic abilities. As discussed in the paper, neither the HAROLD nor the RH decline does fully explain this pattern of results. We rather suggest that the effect of aging on the hemispheric specialization and inter-hemispheric cooperation during semantic processing is explained not by only one model, but by an interaction between several complementary mechanisms and models. •Older are as accurate as younger adults for semantic categorization.•Aging induces increased left-hemispheric predominance with non-semantic RH decline.•Older use different strategies than younger to process the semantic information.