Decrease of arterial stiffness at common carotid artery in hypothyroid patients by normalization of thyroid function

• Published in: Biomedicine & pharmacotherapy Vol. 59; no. 1-2; pp. 8 - 14
• Main Authors: Nagasaki, Toshiki, Inaba, Masaaki, Kumeda, Yasuro, Ueda, Misako, Hiura, Yoshikazu, Tahara, Hideki, Ishimura, Eiji, Onoda, Naoyoshi, Ishikawa, Tetsuro, Nishizawa, Yoshiki
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.01.2005
• Subjects: Arterial stiffness; Carotid Artery, Common - drug effects; Carotid Artery, Common - pathology; Carotid Artery, Common - physiology; Female; Humans; Hypothyroidism; Hypothyroidism - blood; Hypothyroidism - drug therapy; Hypothyroidism - pathology; Intima-media thickness; Male; Middle Aged; Prospective Studies; Regression Analysis; Statistics, Nonparametric; Thyroid Function Tests - statistics & numerical data; Thyroid Gland - drug effects; Thyroid Gland - physiology; Thyroxine - pharmacology; Thyroxine - therapeutic use; Arterial stiffness; Intima-media thickness; Hypothyroidism

This study examined the effect of hypothyroidism on arterial stiffening and the effect of levothyroxine (l-T4) replacement. The arterial stiffness index beta (stiffness β) and intima-media thickness (IMT), a parameter of arterial stiffening and thickening, respectively, were determined in common car...