Reduced task durations in functional PET imaging with [18F]FDG approaching that of functional MRI

• Published in: NeuroImage (Orlando, Fla.) Vol. 181; pp. 323 - 330
• Main Authors: Rischka, Lucas, Gryglewski, Gregor, Pfaff, Sarah, Vanicek, Thomas, Hienert, Marius, Klöbl, Manfred, Hartenbach, Markus, Haug, Alexander, Wadsak, Wolfgang, Mitterhauser, Markus, Hacker, Marcus, Kasper, Siegfried, Lanzenberger, Rupert, Hahn, Andreas
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2018; Elsevier Limited
• Subjects: [18F]FDG; Adult; Brain mapping; Cortex (motor); Cortex (temporal); Energy budget; Female; Fluorodeoxyglucose F18 - administration & dosage; Fluorodeoxyglucose F18 - pharmacokinetics; fMRI; fPET; Functional magnetic resonance imaging; Functional Neuroimaging - methods; Functional PET; Glucose; Glucose metabolism; Humans; Magnetic Resonance Imaging - methods; Male; Medical imaging; Metabolism; Motor Cortex - diagnostic imaging; Motor Cortex - metabolism; Motor Cortex - physiology; Multimodal Imaging; Neuroimaging; NMR; Nuclear magnetic resonance; Positron emission tomography; Positron-Emission Tomography - methods; Psychomotor Performance - physiology; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - pharmacokinetics; Sampling; Sensorimotor integration; Supplementary motor area; Task specific glucose metabolism; Visual cortex; Visual Cortex - diagnostic imaging; Visual Cortex - metabolism; Visual Cortex - physiology; Young Adult; [18F]FDG; fMRI; Task specific glucose metabolism; fPET; Functional PET; [F]FDG

The brain's energy budget can be non-invasively assessed with different imaging modalities such as functional MRI (fMRI) and PET (fPET), which are sensitive to oxygen and glucose demands, respectively. The introduction of hybrid PET/MRI systems further enables the simultaneous acquisition of th...