Kank proteins: A new family of ankyrin-repeat domain-containing proteins

• Published in: Biochimica et biophysica acta Vol. 1780; no. 2; pp. 128 - 133
• Main Authors: Zhu, Yun, Kakinuma, Naoto, Wang, Yong, Kiyama, Ryoiti
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2008
• Subjects: Actin stress fiber; Amino Acid Sequence; Animals; Ankyrin Repeat; Coiled-coil domain; Gene Expression; Genome; Humans; Kank family protein; Mice; Molecular Sequence Data; NIH 3T3 Cells; Phylogeny; Rats; Tumor Suppressor Proteins - chemistry; Tumor Suppressor Proteins - classification; Tumor Suppressor Proteins - genetics; Kank family protein; Actin stress fiber; Coiled-coil domain; Ankyrin repeat

The human Kank gene was found as a candidate tumor suppressor for renal cell carcinoma, and encodes an ankyrin-repeat domain-containing protein, Kank. Here, we report a new family of proteins consisting of three Kank (Kank1)-associated members, Kank2, Kank3 and Kank4, which were found by domain and...