A multi-nozzle nebuliser does not improve tissue drug delivery during PIPAC - Sautkin, Yaroslaw; Weinreich, Juergen; Reymond, Marc André (Surgical endoscopy, 2024)
Keywords: Abdominal Surgery; Administration, Inhalation; Aerosols; Animals; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - pharmacokinetics; Bladder; Cattle; Chemotherapy; Cisplatin - administration & dosage; Cisplatin - pharmacokinetics; Cytotoxicity; Doxorubicin - administration & dosage; Doxorubicin - pharmacokinetics; Drug delivery systems; Drug Delivery Systems - instrumentation; Drugs; Endoscopy; Equipment Design; Experiments; Gastroenterology; Gynecology; Hepatology; Lasers; Medicine; Medicine & Public Health; Nebulizers and Vaporizers; Nozzles; Particle Size; Proctology; Spectrum analysis; Surgery; Tissue Distribution; Urinary Bladder; Intraperitoneal drug delivery; Peritoneal metastasis; Pressurised intraperitoneal aerosol chemotherapy—PIPAC; Nebuliser; Peritoneum