Maraviroc versus Efavirenz, Both in Combination with Zidovudine-Lamivudine, for the Treatment of Antiretroviral-Naive Subjects with CCR5-tropic HIV-1 Infection - Cooper, David A.; Heera, Jayvant; Heera, Jayvant; Goodrich, James; Tawadrous, Margaret; Saag, Michael; DeJesus, Edwin; Clumeck, Nathan; Walmsley, Sharon; Ting, Naitee; Coakley, Eoin; Reeves, Jacqueline D.; et al. (The Journal of infectious diseases, 2010)
Keywords: Adolescent; Adult; Aged; Anti-HIV Agents - pharmacology; Anti-HIV Agents - standards; Anti-Retroviral Agents; Antiviral Agents - pharmacology; Benzoxazines - pharmacology; Benzoxazines - standards; Benzoxazines - therapeutic use; Biological and medical sciences; CCR5 Receptor Antagonists; Cyclohexanes - pharmacology; Cyclohexanes - standards; Cyclohexanes - therapeutic use; Double-Blind Method; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Female; Fundamental and applied biological sciences. Psychology; HIV; HIV 1; HIV Infections - drug therapy; HIV-1 - drug effects; HIV-1 - physiology; HIV/AIDS; Human immunodeficiency virus 1; Human viral diseases; Humans; Infections; Infectious diseases; Lamivudine - administration & dosage; Male; Medical sciences; Microbiology; Middle Aged; Miscellaneous; Post hoc; Receptors, CCR5 - metabolism; Response rates; RNA; Stock options; Treatment Outcome; Triazoles - pharmacology; Triazoles - standards; Triazoles - therapeutic use; Tropisms; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viral Load; Viral Tropism; Virology; Viruses; Young Adult; Zidovudine - administration & dosage; Antiretroviral agent; Benzoxazine derivatives; RNA-directed DNA polymerase; Acetylenic compound; HIV-1 virus; Non nucleoside compound; Efavirenz; Maraviroc; Reverse transcriptase inhibitor; Nucleoside analog; Antiviral; Pyrimidine nucleoside; Immunopathology; Drug combination; Enzyme; Transferases; Enzyme inhibitor; Retroviridae; Lamivudine; AIDS; Immune deficiency; Lentivirus; Infection; Virus; CCR5 chemokine receptor; Allosteric inhibitor; Nucleotidyltransferases; Treatment; Dideoxynucleoside; Viral disease; Human immunodeficiency virus; Zidovudine