Role of the Autism Risk Gene Shank3 in the Development of Atherosclerosis: Insights from Big Data and Mechanistic Analyses - Chang, Hsiu-Wen; Hsu, Ming-Jen; Chien, Li-Nien; Chi, Nai-Fang; Yu, Meng-Chieh; Chen, Hsiu-Chen; Lin, Yuan-Feng; Hu, Chaur-Jong (Cells (Basel, Switzerland), 2023)
Keywords: Animals; Antibodies; Arteriosclerosis; Atherosclerosis; Atherosclerosis - genetics; Autism; autism spectrum disorder; Autism Spectrum Disorder - genetics; Autistic Disorder - genetics; Big Data; Biotechnology; Cardiovascular Diseases; cardiovascular disorder; Cell adhesion molecules; Cholesterol; Down-regulation; Fatty acids; Fatty-acid synthase; Gene expression; Gene set enrichment analysis; Genes; Heart attacks; Homeostasis; Humans; Hyperlipidemia; Hyperlipidemias; Inflammation; Ischemia; Kinases; lipid metabolism; Mice; Microfilament Proteins; Mutation; National health insurance; Nerve Tissue Proteins - genetics; Patients; Penicillin; Polymerase chain reaction; Population studies; Proteins; Shank3; Social interaction; Stroke; Tumor Necrosis Factor-alpha; Tumor necrosis factor-α; Vascular cell adhesion molecule 1; Young Adult; Young adults; United States--US; Taiwan; atherosclerosis; Shank3; autism spectrum disorder; inflammation; cardiovascular disorder; lipid metabolism