Down-regulation of ABCB1 transporter by atorvastatin in a human hepatoma cell line and in human peripheral blood mononuclear cells - Rodrigues, Alice Cristina; Curi, Rui; Britto, Luiz R.G.; Rebbechi, Ivanise M.M.; Hirata, Mario H.; Bertolami, Marcelo C.; Bernik, Marcia M.S.; Dorea, Egidio L.; Hirata, Rosario D.C. (Biochimica et biophysica acta, 2006)
Keywords: ABCB1; ABCB1 mRNA; Atorvastatin; Atorvastatin Calcium; ATP Binding Cassette Transporter, Sub-Family B; ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism; Base Sequence; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; DNA Primers; Down-Regulation - drug effects; Flow Cytometry; HepG2; Heptanoic Acids - pharmacology; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Monocytes - metabolism; Organic Anion Transporters - blood; Organic Anion Transporters - metabolism; PBMC; Pyrroles - pharmacology; Rhodamine 123 - metabolism; RNA, Messenger - genetics; ABCB1 mRNA; Atorvastatin; HepG2; ABCB1; PBMC