diagnostic utility of the anti-CCP antibody test is no better than rheumatoid factor in South Africans with early rheumatoid arthritis

• Published in: Clinical rheumatology Vol. 29; no. 6; pp. 615 - 618
• Main Authors: Hodkinson, Bridget, Meyer, Pieter W. A, Musenge, Eustasius, Ally, Mahmood M. T, Wadee, Ahmed A, Anderson, Ronald, Tikly, Mohammed
• Format: Journal Article
• Language: English
• Published: London London : Springer-Verlag 01.06.2010; Springer-Verlag; Springer Nature B.V
• Subjects: Adult; Africa; African Continental Ancestry Group; Anti-CCP antibodies; Arthritis, Rheumatoid; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - immunology; Autoantibodies; Autoantibodies - immunology; Black People; Blacks; Cross-Sectional Studies; diagnosis; diagnostic use; Female; Humans; immunology; Lupus Erythematosus, Systemic; Lupus Erythematosus, Systemic - diagnosis; Lupus Erythematosus, Systemic - immunology; Male; Medicine; Medicine & Public Health; Middle Aged; Original Article; Peptides, Cyclic; Peptides, Cyclic - immunology; Predictive Value of Tests; Regression Analysis; rheumatoid arthritis; Rheumatoid Factor; Rheumatoid Factor - immunology; Rheumatology; Sensitivity and Specificity; Severity of Illness Index; South Africa; Africa; South Africa; Rheumatoid factor; Blacks; Anti-CCP antibodies; Rheumatoid arthritis; Africa

To establish the diagnostic utility of the anti-cyclic-citrullinated peptide antibody (aCCP) test in Black South Africans with early rheumatoid arthritis (RA). A cross-sectional study comparing the rheumatoid factor (RF) and aCCP status in RA patients and a control group consisting of healthy subjec...