Temporal changes in parameters associated with tear film stability after instillation of long-acting diquafosol ophthalmic solution in soft contact lens wearers

• Published in: Japanese journal of ophthalmology Vol. 69; no. 2; pp. 308 - 315
• Main Authors: Itokawa, Takashi, Suzuki, Takashi, Iwashita, Hiroko, Okajima, Yukinobu, Kakisu, Koji, Hori, Yuichi
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01.03.2025; Springer Nature B.V
• Subjects: Adult; Clinical Investigation; Contact lenses; Contact Lenses, Hydrophilic; Cross-Over Studies; Dry Eye Syndromes - drug therapy; Dry Eye Syndromes - metabolism; Female; Follow-Up Studies; Humans; Male; Medicine; Medicine & Public Health; Ophthalmic Solutions - administration & dosage; Ophthalmology; Parameters; Polyphosphates - administration & dosage; Polyvinylpyrrolidone; Prospective Studies; Purinergic P2Y Receptor Agonists - administration & dosage; Silicones; Stability; Surface temperature; Tears - metabolism; Time Factors; Uracil Nucleotides - administration & dosage; Young Adult; Tear meniscus height; Non-invasive tear break-up time; Soft contact lens; Ocular surface temperature; Long-acting diquafosol ophthalmic solution

Purpose To investigate temporal changes in parameters associated with tear film stability after instillation of long-acting 3% diquafosol ophthalmic solution (DQS LX), which contains polyvinylpyrrolidone. Study Design Prospective crossover study design. Methods We enrolled 23 eyes of 23 soft contact...