Ubiquinol Supplementation of Donor Tissue Enhances Corneal Endothelial Cell Mitochondrial Respiration

• Published in: Cornea Vol. 39; no. 10; p. 1285
• Main Authors: Skeie, Jessica M, Aldrich, Benjamin T, Nishimura, Darryl Y, Schmidt, Gregory A, Zimmerman, M Bridget, Ling, Jennifer J, Naguib, Youssef W, Salem, Aliasger K, Greiner, Mark A
• Format: Journal Article
• Language: English
• Published: United States 01.10.2020

To determine whether ubiquinol improves mitochondrial function and cell viability in human donor corneal endothelial cells during hypothermic corneal tissue storage. Endothelial cell Descemet membrane tissues were treated with 10 μM ubiquinol, the reduced form of the antioxidant coenzyme Q10, for 5...