Totally laparoscopic total proctocolectomy: A safe alternative to open surgery in inflammatory bowel disease

Background: Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL‐TPC) using the perineal wound for extraction a...

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Published inInflammatory bowel diseases Vol. 18; no. 5; pp. 863 - 868
Main Authors Holder‐Murray, Jennifer, Zoccali, Marco, Hurst, Roger D., Umanskiy, Konstantin, Rubin, Michele, Fichera, Alessandro
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.05.2012
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Abstract Background: Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL‐TPC) using the perineal wound for extraction as the procedure of choice in IBD patients who are not candidates for a restorative procedure. This study looks at the TL‐TPC results and compares them with our open cohort. Methods: Prospectively collected data from 52 consecutive patients undergoing TL‐TPC from 2002 to 2010 were compared to 31 contemporary patients undergoing open TPC. Results: Demographics and patient characteristics including body mass index were similar. Mean operative times were 340 ± 7 minutes for TL‐TPC and 337 ± 9 minutes for open TPC (P = 0.91). Intraoperative blood loss was 228 ± 2 mL for TL‐TPC and 484 ± 3 mL for open TPC (P < 0.001). Return of bowel function measured as an ileostomy output >100 mL per 8 hours occurred at 2.7 ± 2.8 days for TL‐TPC versus 3.3 ± 1.8 days for open TPC (P = 0.025). The length of stay was 8.4 ± 5.0 days for TL‐TPC versus 9.2 ± 3.2 days for open TPC (P = 0.05). The overall complication rate was 43% for TL‐TPC versus 65% for open TPC (P = 0.07). Postoperative abdominal wound infections and parastomal hernias occurred in 23% and 10% of open TPC patients, respectively, versus zero (P = 0.001) and 6% (P = 0.67) for TL‐TPC. Conclusions: TL‐TPC is therefore considered a safe alternative to open surgery for selected IBD patients not candidates for a restorative procedure. (Inflamm Bowel Dis 2011;)
AbstractList Background: Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL‐TPC) using the perineal wound for extraction as the procedure of choice in IBD patients who are not candidates for a restorative procedure. This study looks at the TL‐TPC results and compares them with our open cohort. Methods: Prospectively collected data from 52 consecutive patients undergoing TL‐TPC from 2002 to 2010 were compared to 31 contemporary patients undergoing open TPC. Results: Demographics and patient characteristics including body mass index were similar. Mean operative times were 340 ± 7 minutes for TL‐TPC and 337 ± 9 minutes for open TPC (P = 0.91). Intraoperative blood loss was 228 ± 2 mL for TL‐TPC and 484 ± 3 mL for open TPC (P < 0.001). Return of bowel function measured as an ileostomy output >100 mL per 8 hours occurred at 2.7 ± 2.8 days for TL‐TPC versus 3.3 ± 1.8 days for open TPC (P = 0.025). The length of stay was 8.4 ± 5.0 days for TL‐TPC versus 9.2 ± 3.2 days for open TPC (P = 0.05). The overall complication rate was 43% for TL‐TPC versus 65% for open TPC (P = 0.07). Postoperative abdominal wound infections and parastomal hernias occurred in 23% and 10% of open TPC patients, respectively, versus zero (P = 0.001) and 6% (P = 0.67) for TL‐TPC. Conclusions: TL‐TPC is therefore considered a safe alternative to open surgery for selected IBD patients not candidates for a restorative procedure. (Inflamm Bowel Dis 2011;)
BACKGROUNDInflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL-TPC) using the perineal wound for extraction as the procedure of choice in IBD patients who are not candidates for a restorative procedure. This study looks at the TL-TPC results and compares them with our open cohort.METHODSProspectively collected data from 52 consecutive patients undergoing TL-TPC from 2002 to 2010 were compared to 31 contemporary patients undergoing open TPC.RESULTSDemographics and patient characteristics including body mass index were similar. Mean operative times were 340 ± 7 minutes for TL-TPC and 337 ± 9 minutes for open TPC (P = 0.91). Intraoperative blood loss was 228 ± 2 mL for TL-TPC and 484 ± 3 mL for open TPC (P < 0.001). Return of bowel function measured as an ileostomy output >100 mL per 8 hours occurred at 2.7 ± 2.8 days for TL-TPC versus 3.3 ± 1.8 days for open TPC (P = 0.025). The length of stay was 8.4 ± 5.0 days for TL-TPC versus 9.2 ± 3.2 days for open TPC (P = 0.05). The overall complication rate was 43% for TL-TPC versus 65% for open TPC (P = 0.07). Postoperative abdominal wound infections and parastomal hernias occurred in 23% and 10% of open TPC patients, respectively, versus zero (P = 0.001) and 6% (P = 0.67) for TL-TPC.CONCLUSIONSTL-TPC is therefore considered a safe alternative to open surgery for selected IBD patients not candidates for a restorative procedure.
Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL-TPC) using the perineal wound for extraction as the procedure of choice in IBD patients who are not candidates for a restorative procedure. This study looks at the TL-TPC results and compares them with our open cohort. Prospectively collected data from 52 consecutive patients undergoing TL-TPC from 2002 to 2010 were compared to 31 contemporary patients undergoing open TPC. Demographics and patient characteristics including body mass index were similar. Mean operative times were 340 ± 7 minutes for TL-TPC and 337 ± 9 minutes for open TPC (P = 0.91). Intraoperative blood loss was 228 ± 2 mL for TL-TPC and 484 ± 3 mL for open TPC (P < 0.001). Return of bowel function measured as an ileostomy output >100 mL per 8 hours occurred at 2.7 ± 2.8 days for TL-TPC versus 3.3 ± 1.8 days for open TPC (P = 0.025). The length of stay was 8.4 ± 5.0 days for TL-TPC versus 9.2 ± 3.2 days for open TPC (P = 0.05). The overall complication rate was 43% for TL-TPC versus 65% for open TPC (P = 0.07). Postoperative abdominal wound infections and parastomal hernias occurred in 23% and 10% of open TPC patients, respectively, versus zero (P = 0.001) and 6% (P = 0.67) for TL-TPC. TL-TPC is therefore considered a safe alternative to open surgery for selected IBD patients not candidates for a restorative procedure.
Author Holder‐Murray, Jennifer
Fichera, Alessandro
Umanskiy, Konstantin
Rubin, Michele
Zoccali, Marco
Hurst, Roger D.
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Cites_doi 10.1007/s11605-008-0755-9
10.1007/s10350-007-0304-8
10.1007/s10350-004-0587-y
10.1001/archsurg.2009.81
10.1016/S0140-6736(05)66545-2
10.1007/s00104-009-1723-y
10.1007/s004640000356
10.1007/s10350-004-6625-y
10.1002/ibd.20914
10.1089/lps.1992.2.175
10.1007/BF02235570
10.1007/s00464-004-8245-y
10.1016/S1470-2045(05)70221-7
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References 2009; 13
2005; 19
2009; 80
2005; 365
2000; 43
2004; 47
2003; 46
2009; 144
2005; 6
2005
2001; 15
2007; 50
2001; 44
1992; 2
1995; 5
2009; 15
Guillou (R1-11-20130704) 2005; 365
Kroesen (R13-11-20130704) 2009; 80
Peters (R9-11-20130704) 1992; 2
Thibault (R10-11-20130704) 1995; 5
Fichera (R15-11-20130704) 2003; 46
James (R16-11-20130704) 2009; 144
Boushey (R5-11-20130704) 2007; 50
Seshadri (R11-11-20130704) 2001; 15
Marcello (R6-11-20130704) 2000; 43
Fichera (R4-11-20130704) 2009; 13
Rivadeneira (R7-11-20130704) 2004; 47
Veldkamp (R2-11-20130704) 2005; 6
Larson (R8-11-20130704) 2005; 19
Holubar (R12-11-20130704) 2009; 15
References_xml – volume: 6
  start-page: 477
  year: 2005
  end-page: 484
  article-title: Laparoscopic surgery versus open surgery for colon cancer: short‐term outcomes of a randomised trial
  publication-title: Lancet Oncol.
– start-page: CD003145
  year: 2005
  article-title: Short term benefits for laparoscopic colorectal resection
  publication-title: Cochrane Database Syst Rev.
– volume: 13
  start-page: 526
  year: 2009
  end-page: 532
  article-title: Laparoscopic restorative proctocolectomy with ileal pouch anal anastomosis: a comparative observational study on long‐term functional results
  publication-title: J Gastrointest Surg.
– volume: 2
  start-page: 175
  year: 1992
  end-page: 178
  article-title: Laparoscopic total proctocolectomy with creation of ileostomy for ulcerative colitis: report of two cases
  publication-title: J Laparoendosc Surg.
– volume: 15
  start-page: 837
  year: 2001
  end-page: 842
  article-title: Does a laparoscopic approach to total abdominal colectomy and proctocolectomy offer advantages?
  publication-title: Surg Endosc.
– volume: 80
  start-page: 730
  year: 2009
  end-page: 733
  article-title: [Therapy of refractory proctocolitis and Crohn's disease. Incisionless laparoscopic proctocolectomy with a Brooke ileostomy.]
  publication-title: Chirurg.
– volume: 365
  start-page: 1718
  year: 2005
  end-page: 1726
  article-title: Short‐term endpoints of conventional versus laparoscopic‐assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial
  publication-title: Lancet.
– volume: 47
  start-page: 1371
  year: 2004
  end-page: 1376
  article-title: Benefits of hand‐assisted laparoscopic restorative proctocolectomy: a comparative study
  publication-title: Dis Colon Rectum.
– volume: 15
  start-page: 1337
  year: 2009
  end-page: 1342
  article-title: Minimally invasive total proctocolectomy with Brooke ileostomy for ulcerative colitis
  publication-title: Inflamm Bowel Dis.
– volume: 19
  start-page: 1284
  year: 2005
  end-page: 1287
  article-title: Total laparoscopic proctocolectomy with Brooke ileostomy: a novel incisionless surgical treatment for patients with ulcerative colitis
  publication-title: Surg Endosc.
– volume: 5
  start-page: 472
  year: 1995
  end-page: 476
  article-title: Total laparoscopic proctocolectomy and laparoscopy‐assisted proctocolectomy for inflammatory bowel disease: operative technique and preliminary report
  publication-title: Surg Laparosc Endosc.
– volume: 144
  start-page: 520
  year: 2009
  end-page: 526
  article-title: Portomesenteric venous thrombosis after laparoscopic surgery: a systematic literature review
  publication-title: Arch Surg.
– volume: 44
  start-page: 1
  year: 2001
  end-page: 8
  article-title: Prospective, randomized trial comparing laparoscopic vs. conventional surgery for refractory ileocolic Crohn's disease
  publication-title: Dis Colon Rectum.
– volume: 46
  start-page: 643
  year: 2003
  end-page: 648
  article-title: Superior mesenteric vein thrombosis after colectomy for inflammatory bowel disease: a not uncommon cause of postoperative acute abdominal pain
  publication-title: Dis Colon Rectum.
– volume: 50
  start-page: 1512
  year: 2007
  end-page: 1519
  article-title: Laparoscopic total colectomy: an evolutionary experience
  publication-title: Dis Colon Rectum.
– volume: 43
  start-page: 604
  year: 2000
  end-page: 608
  article-title: Laparoscopic restorative proctocolectomy: case‐matched comparative study with open restorative proctocolectomy
  publication-title: Dis Colon Rectum.
– volume: 13
  start-page: 526
  year: 2009
  ident: R4-11-20130704
  publication-title: J Gastrointest Surg
  doi: 10.1007/s11605-008-0755-9
  contributor:
    fullname: Fichera
– volume: 5
  start-page: 472
  year: 1995
  ident: R10-11-20130704
  publication-title: Surg Laparosc Endosc
  contributor:
    fullname: Thibault
– volume: 50
  start-page: 1512
  year: 2007
  ident: R5-11-20130704
  publication-title: Dis Colon Rectum
  doi: 10.1007/s10350-007-0304-8
  contributor:
    fullname: Boushey
– volume: 47
  start-page: 1371
  year: 2004
  ident: R7-11-20130704
  publication-title: Dis Colon Rectum
  doi: 10.1007/s10350-004-0587-y
  contributor:
    fullname: Rivadeneira
– volume: 144
  start-page: 520
  year: 2009
  ident: R16-11-20130704
  publication-title: Arch Surg
  doi: 10.1001/archsurg.2009.81
  contributor:
    fullname: James
– volume: 365
  start-page: 1718
  year: 2005
  ident: R1-11-20130704
  publication-title: Lancet
  doi: 10.1016/S0140-6736(05)66545-2
  contributor:
    fullname: Guillou
– volume: 80
  start-page: 730
  year: 2009
  ident: R13-11-20130704
  publication-title: Chirurg
  doi: 10.1007/s00104-009-1723-y
  contributor:
    fullname: Kroesen
– volume: 15
  start-page: 837
  year: 2001
  ident: R11-11-20130704
  publication-title: Surg Endosc
  doi: 10.1007/s004640000356
  contributor:
    fullname: Seshadri
– volume: 46
  start-page: 643
  year: 2003
  ident: R15-11-20130704
  publication-title: Dis Colon Rectum
  doi: 10.1007/s10350-004-6625-y
  contributor:
    fullname: Fichera
– volume: 15
  start-page: 1337
  year: 2009
  ident: R12-11-20130704
  publication-title: Inflamm Bowel Dis
  doi: 10.1002/ibd.20914
  contributor:
    fullname: Holubar
– volume: 2
  start-page: 175
  year: 1992
  ident: R9-11-20130704
  publication-title: J Laparoendosc Surg
  doi: 10.1089/lps.1992.2.175
  contributor:
    fullname: Peters
– volume: 43
  start-page: 604
  year: 2000
  ident: R6-11-20130704
  publication-title: Dis Colon Rectum
  doi: 10.1007/BF02235570
  contributor:
    fullname: Marcello
– volume: 19
  start-page: 1284
  year: 2005
  ident: R8-11-20130704
  publication-title: Surg Endosc
  doi: 10.1007/s00464-004-8245-y
  contributor:
    fullname: Larson
– volume: 6
  start-page: 477
  year: 2005
  ident: R2-11-20130704
  publication-title: Lancet Oncol
  doi: 10.1016/S1470-2045(05)70221-7
  contributor:
    fullname: Veldkamp
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Snippet Background: Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach...
Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could...
BACKGROUNDInflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach...
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SubjectTerms Colectomy
Colitis, Ulcerative - surgery
Crohn Disease - surgery
Crohn's disease
Female
Follow-Up Studies
Humans
inflammatory bowel disease
Intestinal Perforation
laparoscopic
Laparoscopy
Male
Middle Aged
Proctocolectomy
Proctocolectomy, Restorative
Prognosis
Prospective Studies
Retrospective Studies
Risk Factors
ulcerative colitis
Title Totally laparoscopic total proctocolectomy: A safe alternative to open surgery in inflammatory bowel disease
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fibd.21808
https://www.ncbi.nlm.nih.gov/pubmed/21761510
https://search.proquest.com/docview/1000407434
Volume 18
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