Enhanced Nanodrug Delivery to Solid Tumors Based on a Tumor Vasculature-Targeted Strategy

• Published in: Advanced functional materials Vol. 26; no. 23; pp. 4192 - 4200
• Main Authors: Song, Chenghua, Zhang, Yejun, Li, Chunyan, Chen, Guangcun, Kang, Xiaofeng, Wang, Qiangbin
• Format: Journal Article
• Language: English
• Published: Blackwell Publishing Ltd 20.06.2016
• Subjects: Ag2S quantum dots; Fluorescence; Imaging; Inhibition; Nanostructure; near-infrared fluorescence; Peptides; Strategy; Therapy; tumor angiogenesis; tumor therapy; Tumors; vasculature-targeted

Tumor angiogenesis is a hallmark of tumor growth and metastasis, and inhibition of tumor angiogenesis is an effective strategy for tumor therapy. The high expression levels of specific biomarkers such as integrin receptors (e.g., αvβ3) in the endothelium of tumor vessels make angiogenesis an ideal t...