Outer membrane vesicles produced by Burkholderia cepacia cultured with subinhibitory concentrations of ceftazidime enhance pro-inflammatory responses

• Published in: Virulence Vol. 11; no. 1; pp. 995 - 1005
• Main Authors: Kim, Se Yeon, Kim, Mi Hyun, Son, Joo Hee, Kim, Seung Il, Yun, Sung Ho, Kim, Kyeongmin, Kim, Shukho, Shin, Minsang, Lee, Je Chul
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 31.12.2020; Taylor & Francis Group
• Subjects: antibiotics; Burkholderia cepacia; cytotoxicity; inflammatory response; outer membrane vesicle; Research Paper

Burkholderia cepacia is an opportunistic pathogen that infects patients with debilitating underlying diseases. This study investigated the production of outer membrane vesicles (OMVs) by B. cepacia cultured with sub-minimum inhibitory concentrations (MICs) of antibiotics and examined their pathogeni...