Lactate measurements in sepsis-induced tissue hypoperfusion: results from the Surviving Sepsis Campaign database

• Published in: Critical care medicine Vol. 43; no. 3; p. 567
• Main Authors: Casserly, Brian, Phillips, Gary S, Schorr, Christa, Dellinger, R Phillip, Townsend, Sean R, Osborn, Tiffany M, Reinhart, Konrad, Selvakumar, Narendran, Levy, Mitchell M
• Format: Journal Article
• Language: English
• Published: United States 01.03.2015
• Subjects: Biomarkers; Clinical Protocols; Hospital Mortality; Humans; Hypotension - epidemiology; Lactates - blood; Quality Improvement; Sepsis - blood; Sepsis - mortality; Sepsis - therapy; Shock, Septic - blood; Shock, Septic - mortality

The Surviving Sepsis Campaign guidelines recommend obtaining a serum lactate measurement within 6 hours of presentation for all patients with suspected severe sepsis or septic shock. A lactate greater than 4 mmol/L qualifies for administration of early quantitative resuscitation therapy. We evaluate...