The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers

• Published in: International journal of cancer Vol. 131; no. 5; pp. E733 - E743
• Main Authors: Lee, Chien-Hung, Lee, Ka-Wo, Fang, Fu-Min, Wu, Deng-Chyang, Tsai, Shih-Meng, Chen, Ping-Ho, Shieh, Tien-Yu, Chen, Chung-Ho, Wu, I-Chen, Huang, Hsiao-Ling, Chen, Bai-Hsiun, Chang, Cheng-Hsien, Chen, Mu-Kuan, Chou, Shah-Hwa, Tsai, Yi-Shan, Chiang, Shang-Lun, Ko, Ying-Chin
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2012; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; alcohol drinking; Alcohol Drinking - adverse effects; anatomical site; Areca - adverse effects; areca nut; Cancer; Carcinogens - pharmacology; Carcinoma, Squamous Cell - epidemiology; Carcinoma, Squamous Cell - etiology; Carcinoma, Squamous Cell - pathology; Case-Control Studies; Esophageal Neoplasms - epidemiology; Esophageal Neoplasms - etiology; Esophageal Neoplasms - pathology; Female; Follow-Up Studies; Gastric cancer; gastrointestinal cancer; Gastrointestinal Neoplasms - epidemiology; Gastrointestinal Neoplasms - etiology; Gastrointestinal Neoplasms - pathology; Histology; Humans; Incidence; Laryngeal Neoplasms - epidemiology; Laryngeal Neoplasms - etiology; Laryngeal Neoplasms - pathology; Male; Medical research; Middle Aged; Pharyngeal Neoplasms - epidemiology; Pharyngeal Neoplasms - etiology; Pharyngeal Neoplasms - pathology; Prognosis; Risk Factors; Smoking - adverse effects; Taiwan - epidemiology; Tobacco; tobacco smoking; upper aerodigestive cancer; Taiwan

Little is known about any consequences of swallowing tobacco‐free betel‐quid (TF‐BQ) juice/remnants following chewing and its carcinogenic impact on the upper aerodigestive tract (UADT) to gastrointestinal tract (GIT). We investigated the neoplastic impact of TF‐BQ on different anatomical locations...