IL6‐mediated inflammatory loop reprograms normal to epithelial‐mesenchymal transition+ metastatic cancer stem cells in preneoplastic liver of transforming growth factor beta–deficient β2‐spectrin+/− mice - Mitra, Abhisek; Yan, Jun; Xia, Xueqing; Zhou, Shouhao; Chen, Jian; Mishra, Lopa; Li, Shulin (Hepatology (Baltimore, Md.), 2017)
Keywords: Animals; Biopsy, Needle; Blotting, Western; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; Cell Transformation, Neoplastic - genetics; Disease Models, Animal; Epithelial-Mesenchymal Transition - genetics; Female; Humans; Immunohistochemistry; Interleukin-6 - pharmacology; Liver Neoplasms - metabolism; Liver Neoplasms - pathology; MAP Kinase Kinase Kinases - drug effects; MAP Kinase Kinase Kinases - metabolism; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells - metabolism; Random Allocation; Statistics, Nonparametric; Transforming Growth Factor beta1 - drug effects; Transforming Growth Factor beta1 - metabolism