Effect of antidepressant treatment on peripheral inflammation markers – A meta-analysis

• Published in: Progress in neuro-psychopharmacology & biological psychiatry Vol. 80; no. Pt C; pp. 217 - 226
• Main Authors: Więdłocha, Magdalena, Marcinowicz, Piotr, Krupa, Renata, Janoska-Jaździk, Marlena, Janus, Marta, Dębowska, Weronika, Mosiołek, Anna, Waszkiewicz, Napoleon, Szulc, Agata
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 03.01.2018
• Subjects: Antidepressants; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Biomarkers - blood; Cytokines; Cytokines - blood; Depression; Depressive Disorder, Major - blood; Depressive Disorder, Major - drug therapy; Depressive Disorder, Major - immunology; Female; Humans; Inflammation; Inflammation Mediators - blood; Male; Meta-analysis; Depression; Inflammation; Cytokines; Antidepressants; Meta-analysis

Major Depressive Disorder (MDD) in accordance to the inflammatory concept is associated with complex immunological disturbances in the central nervous system (CNS). This is reflected by elevated plasma levels of inflammatory cytokines in depressed subjects. Although numerous studies report significa...